Unleashing the Power of Genomics for Accurate Microbial Identification
Industries We Support
Biopharmaceuticals
Clinical Diagnostics
Food & Beverage
Research & Development
With Accurate Microbial ID Sequencing Solutions
Micro Identification
Identify, Track & Link microbiological contaminants in your facility
Accurate microbial identification is the cornerstone of successful biopharmaceutical manufacturing, safeguarding processes where contamination risks are ever-present. At ELDA Biotech, we specialise in advanced sequencing technologies, including 16S rRNA Sanger sequencing and Whole Genome Sequencing (WGS) to pinpoint, trace, and understand microbial contaminants with unmatched precision.
Our services go beyond basic identification, offering the insights needed to track contamination pathways, establish clear links between microbial sources, and enhance quality control measures. These solutions are tailored to the unique demands of the biopharma industry, empowering companies to maintain robust regulatory compliance and ensure the integrity of their operations and products. Whether managing recurrent contamination, investigating CAPAs, validating clean rooms, or conducting confirmatory testing, we offer a range of services from routine isolate ID to advanced microbial profiling solutions.
Setting the Standard for Accurate Microbial Identification
At the forefront of microbial identification, we provide unmatched expertise and precision to support your critical processes such as;
- Confirmatory ID testing
- CAPA & Investigation support
- Clean room validation
- Contamination source tracking
- Environmental monitoring
microbial sequencing & Identification
Microbial Whole Genome Sequencing
Whole Genome Sequencing (WGS) sets a new standard in microbial identification by combining unmatched accuracy, a broader detection range, and the ability to identify multiple microorganisms in a single sample. Delivering high-resolution data, WGS detects microorganisms at species and strain levels, including ultra-rare genetic variants, making it essential for detailed microbial profiling and contamination control. Unlike traditional ID methods, limited to phenotypic characteristics and specific biochemical tests, or Sanger sequencing, which targets predefined gene regions, WGS provides comprehensive insights without prior knowledge of target organisms. This transformative approach accelerates contamination resolution, enhances product safety, and ensures compliance with stringent industry regulations, safeguarding operational integrity across various sectors.
Microorganism Identification
16S and 18S Sanger Sequencing for Microbial Identification
Our 16S bacterial and 18S fungal rRNA sanger sequencing service delivers species-level microbial identification, ensuring accurate and reliable results for bacterial and fungal isolates.Leveraging highly conserved 16S and 18S rRNA genes, our sequencing solutions provide unparalleled accuracy, stability, and reproducibility in microbial identification. Designed for industries like food & beverage processing, biopharmaceuticals, and healthcare, our comprehensive microbial identification services support regulatory compliance and contamination control. By utilising DNA-free reagents, a broad-spectrum 16S/18S PCR is conducted, followed by high-precision Sanger sequencing. Our reliable workflows strengthen contamination control measures and enhance quality assurance programs, critical for maintaining industry standards.
Why outsource microbial ID sequencing services?
Outsourcing to expert microbial identification services grants you the benefits of cutting-edge technologies, validated workflows, and specialised analysis, delivering precise results while optimising your resources and time through access to;
- CE-IVD certified DNA free microbial extraction reagents.
- Validated workflows to guarantee precision, reliability, and regulatory compliance..
- Purpose-built laboratories for microbial sequencing with unidirectional workflows
- State-of-the-Art equipment with HEPA filtration, temperature monitoring, and advanced contamination control measures
- Adherence to ISO standards to meet the highest industry benchmarks.
- Experienced team of microbial sequencing specialists ensuring accurate and reliable results.
Creating purposeful work
with customised solutions
It takes two...
While reference genomes are invaluable, they may not always provide the complete picture for a specific organism. In this study, we showcased the power of integrating both long and short-read sequencing technologies to generate de-novo reference genomes. Specifically, we applied this approach to 22 S. cerevisiae yeast strains, including 16 from the Guinness collection and 6 from historical Irish brewing. This enabled us to accurately trace the origins of the Guinness yeast back tHROUGHOUT THE 1900’s, revealing its unique genetic identity separate from other historical Irish yeasts. Our findings illustrate that combining these two sequencing methods can offer a more detailed and precise understanding of your strain of interest.
The origins of the Guinness stout yeast
The present yeast used to make Guinness stout brewed in Dublin, Ireland, can be traced back throughout the 1900’s, but its origins are unknown. Using Illumina and Nanopore sequencing to generate whole-genome sequencing data the origins of the Guinness yeast were determined with a SNP-based analysis, demonstrating that the Guinness strains occupy a distinct group separate from other historical Irish brewing yeasts.
Clinical SARS-COV-2 Whole Genome Sequencing
Whole genome sequence analysis of SARS-CoV-2
Since 2021, our experienced team has been a reliable partner of the HSE in the crucial task of SARS-CoV-2 genome sequencing. In collaboration with Enfer Medical, Ireland’s leading clinical diagnostic laboratory, we have streamlined the process for rapid and precise Whole Genome Sequencing (WGS) of SARS-CoV-2 clinical samples. Our efficient analysis of COVID-19 sequencing data enabled effective monitoring of the pandemic, focusing on the detection of significant variants and tracking the virus’s evolution in our population. Working alongside the Health Protection Surveillance Centre, we consistently provided up-to-date genomic insights on the circulating SARS-CoV-2 strains in Ireland.
Genomic Analytics
Sequencing of proprietary organisms
Map out the genetic structure of your production organism, crucial for IP protection and security of your asset. Delving deeper, we unravel the complex relationship between genotype and product phenotype. Our expertise lies in matching the intricacies of genetic makeup with the observable traits that define a product to ensure complete characterisation of your high value resource.
Let the DNA tell its story
Through utilising our cutting-edge technologies and advanced analysis capabilities, we link genotype and phenotype by analysing from the nucleic acid to protein level. This scrutinisation of the genetic code deciphers the blueprint that shapes the characterisation of a product.
We've only just begun exploring...
Our specialist pathogen and contaminant identification service plays a crucial role in maintaining the integrity, quality, and safety of various industries.
Specialist microorganism identification service
By identifying potential risks and sources of contamination, we empower our clients to take proactive measures to ensure high-quality process, production, and product safety.
What's in your environment?
With our advanced sequencing technologies and analytical expertise, we characterise the microorganism profile of your environment.
sequencing & Identification
Sequencing & genetic similarity analysis
Uncovering important insights into the resistance and persistence of microorganisms in your industry before they expose you.
Bioinformatics
Bioinformatic analysis
Development of methods and tools to interrogate and interpret complex sequence data.
The powerhouse of data analysis
Bioinformatic analysis is the backbone of our genomic exploration. With cutting-edge computational methods utilising high-performance computing, we extract valuable insights from the sea of genomic data. From DNA sequencing to transcriptomics and beyond, we employ bioinformatic techniques to decipher the language of life and harness its potential.
Oil & Gas
Identify and mitigate microbially induced corrosion in your oil and gas infrastructure with our advanced genomic analysis. Our service precisely pinpoints MIC sources, enhancing asset longevity and operational safety.
Clinical Genomics
Our specialist bacterial identification service uses metagenomic sequencing to detected bacterial DNA in clinical specimens, enabling the broad detection of various pathogens without specific targeting. This technique is especially valuable in diagnosing challenging conditions like where the infectious cause is suspected but remains undetected by conventional methods.
The assay offered by Enfer Medical is the llumina, CovidSeq assay for patients with PCR confirmed COVID-19 infection. The amplicon-based next generation amplicon sequencing (NGS) assay leverages a modified version of the publicly available ARTIC multiplex PCR protocol to help identify novel strains of SARS-CoV-2. The service is clinically validated for nasopharyngeal and oropharyngeal swabs with detectable SARS-CoV-2 RNA.
Discover the unique factors shaping your gut microbiome’s diversity with our microbiome sequencing test. Leveraging the power of Next-generation Sequencing, our microbiome test offers a comprehensive survey of your gut’s microbial genomes, including unculturable organisms, to provide a deeper understanding of your gut health.
Biopharmaceuticals
Ensure the highest standards of safety and quality in your biopharma products with our comprehensive sterile and non-sterile testing. Our genomic analysis detects and monitors microbial presence, guaranteeing product integrity.
Leverage our advanced genomic technologies for precise identification and typing of microorganisms. This service is essential for pathogen characterization, aiding in drug development and ensuring batch-to-batch consistency.
Environmental
Track & Trace
Optimise the safety and compliance of your manufacture environment with our specialised environmental monitoring service. Utilising pathogen genomic analysis, we precisely track and manage microbial activity to prevent contamination risks in critical processes. This targeted approach is crucial for maintaining the stringent cleanliness and quality standards.
